ALK5-IN-85
ALK5-IN-85 (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 [1].
Product Specifications
CAS Number
[2766583-86-0]
UNSPSC
12352005
Target
TGF-β Receptor
Related Pathways
TGF-beta/Smad
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(C1=CC(NC(CN2N=C(C(C3=C4C=CC=CC4=NC=C3)=C2)C5=CC=CC(C)=N5)=O)=CC(F)=C1)OCCN6CCNCC6
Molecular Formula
C33H32FN7O3
Molecular Weight
593.65
References & Citations
[1]BOSSER ARTAL R, et al. 2- (3-pyridin-2-yl-4-quinolin-4-yl-pyrazol-1-yl) -acetamide derivatives as inhibitors of transforming growth factor-beta receptor i/alk5. WO2022069509A1. 2022-04-07.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALK5
Curated Selection
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