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JLJ648

JLJ648 is a Gag-Pol dimerizer with antiviral activity. JLJ648 can inhibit HIV replication and induce infected cell pyroptosis. JLJ648 can be used for the research of infection, such as HIV (human immunodeficiency virus) [1].

Product Specifications

UNSPSC

12352005

Target

HIV; Pyroptosis

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation

Field of Research

Infection

Smiles

S=C(N1)C=CN(CCOC2=C(OC3=CC=CC4=C3C=CC(C#N)=C4)C=CC=C2)C1=O

Molecular Formula

C23H17N3O3S

Molecular Weight

415.46

References & Citations

[1]Hollander K, et al. Mechanistic basis for a novel dual-function Gag-Pol dimerizer potentiating CARD8 inflammasome activation and clearance of HIV-infected cells. NPJ Drug Discov. 2025;2 (1) :22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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