JLJ648
JLJ648 is a Gag-Pol dimerizer with antiviral activity. JLJ648 can inhibit HIV replication and induce infected cell pyroptosis. JLJ648 can be used for the research of infection, such as HIV (human immunodeficiency virus) [1].
Product Specifications
UNSPSC
12352005
Target
HIV; Pyroptosis
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation
Field of Research
Infection
Smiles
S=C(N1)C=CN(CCOC2=C(OC3=CC=CC4=C3C=CC(C#N)=C4)C=CC=C2)C1=O
Molecular Formula
C23H17N3O3S
Molecular Weight
415.46
References & Citations
[1]Hollander K, et al. Mechanistic basis for a novel dual-function Gag-Pol dimerizer potentiating CARD8 inflammasome activation and clearance of HIV-infected cells. NPJ Drug Discov. 2025;2 (1) :22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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