SDH-IN-32
SDH-IN-32 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.74 μM. SDH-IN-32 exhibits excellent antifungal activity. SDH-IN-32 can destroy the cell membrane structure and increase the permeability of the cell membrane. SDH-IN-32 can decrease the mitochondrial membrane potential (MMP), thereby inducing cell apoptosis and inhibiting the normal growth of mycelia. SDH-IN-32 can be used for the research of infection[1].
Product Specifications
UNSPSC
12352101
Target
Apoptosis; Fungal; MMP
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(NNC1=CC=C(F)C=C1)COC2=C(C)CC(C)(C)CC2=O
Molecular Formula
C17H21FN2O3
Molecular Weight
320.36
References & Citations
[1]Chen H, et al. Discovery of Novel Isophorone Derivatives as Potential Succinate Dehydrogenase Inhibitors: Design, Synthesis, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2025 Sep 24;73 (38) :24416-24426.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9369429-01 48 Well
Horse Transient Receptor Potential Cation Channel Subfamily V, Member 4 (TRPV4) ELISA Kit
Ask
View Details 
MBS9369429-02 96 Well
Horse Transient Receptor Potential Cation Channel Subfamily V, Member 4 (TRPV4) ELISA Kit
Ask
View Details 
MBS9369429-03 5x 96 Well
Horse Transient Receptor Potential Cation Channel Subfamily V, Member 4 (TRPV4) ELISA Kit
Ask
View Details MBS9369429-04 10x 96 Well
Horse Transient Receptor Potential Cation Channel Subfamily V, Member 4 (TRPV4) ELISA Kit
Ask
View Details 132404-PE 100 µL
RBM9 (RNA Binding Motif Protein 9, RNA Binding Protein 9, Hexaribonucleotide Binding Protein 2, HRNBP2, Repressor of Tamoxifen Transcriptional Activity, RTA) (PE)
Ask
View Details