TPG-20A
TPG-20A is a SARS-CoV-2 main protease inhibitor with an IC50 of 27.8 nM. TPG-20A also inhibits MERS-CoV main protease. TPG-20A can be used for the research of infection, such as SARS-CoV-2[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C(N1)=CC2=C1C=CC=C2OC)N[C@@H](CC(C)C)C(NN(C(C(Cl)Cl)=O)CC3=CC=CNC3=O)=O
Molecular Formula
C24H27Cl2N5O5
Molecular Weight
536.41
References & Citations
[1]Flury P, et al. Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity. J Med Chem. 2025 Sep 25;68 (18) :19339-19376.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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