α-Amylase/α-Glucosidase-IN-22

α-Amylase/α-Glucosidase-IN-22 is an inhibitor of α-Amylase and α-Glucosidase with IC50 values of 1.71 and 10.36 nM (5 and 23.8 folds more potent than Acarbose (HY-B0089) ) . α-Amylase/α-Glucosidase-IN-22 can be used for the researches of metabolic disease, such as diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C(NC1=CC=C(F)C=C1)CSC2=NC3=CC=CC=C3C=C2/C=N/NC(CCC4=NC(C=CC=C5)=C5N4)=O

Molecular Formula

C28H23FN6O2S

Molecular Weight

526.58

References & Citations

[1]Nikfar P, et al. Introduction of new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives as new α-glucosidase and α-amylase inhibitors. Sci Rep. 2025 Aug 26;15 (1) :31349.