CYP51-IN-27

CYP51-IN-27 is a sterol 14α-demethylase CYP51 inhibitor with an IC50 of 0.3434 μg/mL. CYP51-IN-27 exhibits antifungal activity and inhibits the production of fungal ergosterol. CYP51-IN-27 can be used for the research of infection, such as rice sheath blight[1].

Product Specifications

UNSPSC

12352005

Target

Cytochrome P450; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

N#CNC(N=C/12)=NC(C3=CC(F)=C(F)C(F)=C3)=C2CCCC1=C/C4=CC(F)=C(F)C(F)=C4

Molecular Formula

C22H12F6N4

Molecular Weight

446.35

References & Citations

[1]Deng ZQ, et al. Antifungal Activity of Novel 5,6,7,8-Tetrahydroquinazolin Derivatives against Plant Pathogenic Fungi by Targeting Sterol 14α-Demethylase (CYP51) and the Application on Rice. J Agric Food Chem. 2025 Sep 24;73 (38) :24392-24403.