CYP51-IN-27
CYP51-IN-27 is a sterol 14α-demethylase CYP51 inhibitor with an IC50 of 0.3434 μg/mL. CYP51-IN-27 exhibits antifungal activity and inhibits the production of fungal ergosterol. CYP51-IN-27 can be used for the research of infection, such as rice sheath blight[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
N#CNC(N=C/12)=NC(C3=CC(F)=C(F)C(F)=C3)=C2CCCC1=C/C4=CC(F)=C(F)C(F)=C4
Molecular Formula
C22H12F6N4
Molecular Weight
446.35
References & Citations
[1]Deng ZQ, et al. Antifungal Activity of Novel 5,6,7,8-Tetrahydroquinazolin Derivatives against Plant Pathogenic Fungi by Targeting Sterol 14α-Demethylase (CYP51) and the Application on Rice. J Agric Food Chem. 2025 Sep 24;73 (38) :24392-24403.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP51
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