DHODH-IN-31
DHODH-IN-31 is a human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.59 μM. DHODH-IN-31 exhibits antiviral activity. DHODH-IN-31 can be used for the research of infection, such as SARS-CoV-2[1].
Product Specifications
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; SARS-CoV
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1NC(NC2=CC(C3=CC=CC=C3)=CC=C2)=NC4=C1C=CC=C4
Molecular Formula
C20H15N3O
Molecular Weight
313.35
References & Citations
[1]Bruna F. Godoi, et al. Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties. ACS Medicinal Chemistry Letters Article ASAP
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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