MAO-A/B-IN-5
MAO-A/B-IN-5 is an orally active MAO-A (IC50 = 73.88 μM) and MAO-B (IC50 = 91.08 μM) inhibitor. MAO-A/B-IN-5 reverses Sodium nitroprusside (SNP) -induced cerebral lipid peroxidation (IC50 = 130.2 μM) and protein carbonylation (IC50 = 229.8 μM). MAO-A/B-IN-5 shows dose-dependent and time-dependent antidepressant-like efficacy in mice. MAO-A/B-IN-5 can be used for the study of depressive disorder[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC1=CC=C(C(C[N+]2=CC=CC=C2C[Se]C3=CC=CC=C3)=O)C=C1.[Br-]
Molecular Formula
C21H20BrNOSe
Molecular Weight
461.25
References & Citations
[1]Paim MP, et al. Antidepressant-like Properties of a Selenium-Containing Pyridinium Salt Explored through In Vitro, In Vivo, and In Silico Approaches. ACS Chem Neurosci. 2025 Oct 1;16 (19) :3713-3727.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Frequently Asked Questions
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