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Mc-Lys (PEG12) -Cap-Ala-Ala-PABC

Mc-Lys (PEG12) -Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly- (R) -Cyclopropane-Exatecan.

Product Specifications

UNSPSC

12352005

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

OC(OCC1=CC=C(C=C1)NC([C@@H](NC([C@@H](NC(CCCCCNC([C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C)=O)C)=O)=O

Molecular Formula

C62H103N7O23

Molecular Weight

1314.51

References & Citations

[1]Auvert E, et al. Development of Optimized Exatecan-Based Immunoconjugates with Potent Antitumor Efficacy in HER2-Positive Breast Cancer. J Med Chem. 2025 Sep 25;68 (18) :19122-19142.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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