Mc-Lys (PEG12) -Cap-Ala-Ala-PABC
Mc-Lys (PEG12) -Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly- (R) -Cyclopropane-Exatecan (HY-178146) [1].
Product Specifications
UNSPSC
12352005
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
OC(OCC1=CC=C(C=C1)NC([C@@H](NC([C@@H](NC(CCCCCNC([C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C)=O)C)=O)=O
Molecular Formula
C62H103N7O23
Molecular Weight
1314.51
References & Citations
[1]Auvert E, et al. Development of Optimized Exatecan-Based Immunoconjugates with Potent Antitumor Efficacy in HER2-Positive Breast Cancer. J Med Chem. 2025 Sep 25;68 (18) :19122-19142.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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