SCR005

SCR005 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR005 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR005 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR005 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR005 can be used for the study and prevention of enveloped virus pandemics[1].

Product Specifications

CAS Number

[2409183-70-4]

UNSPSC

12352005

Target

Filovirus; Hepatitis E Virus (HEV) ; SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C1(C/N=C/C2=CC=CN2)=CC(C3=CC(C/N=C/C4=CC=CN4)=CC(C/N=C/C5=CC=CN5)=C3)=CC(C/N=C/C6=CC=CN6)=C1

Molecular Formula

C36H34N8

Molecular Weight

578.71

References & Citations

[1]Ezzatpour S, et al. Broad-spectrum synthetic carbohydrate receptors (SCRs) inhibit viral entry across multiple virus families. Sci Adv. 2025 Aug 29;11 (35) :eady3554.