Anti-MRSA agent 35
Anti-MRSA agent 35 (Compound 6b) is an anti-MRSA agent. Anti-MRSA agent 35 significantly inhibits MRSA biofilm formation, suppresses penicillin-binding protein (PBP2a) expression and induces mecA virulence gene mutation. Anti-MRSA agent 35 has potent bactericidal and fungicidal activities with MIC50s of 7.8-31.25 μg/mL for gram positive bacteria, gram-negative bacteria and Fungi. [1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Fungal; Penicillin-binding protein (PBP)
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
COC(C1=CC=CC=C1/N=N/C2=C(/N=C/C3=CC=C(N(C)C)C=C3)NN=C2N)=O
Molecular Formula
C20H21N7O2
Molecular Weight
391.43
References & Citations
[1]Ragab A, et al. Development of pyrazole and pyrazolopyrimidine derivatives as promising anti-MRSA agents targeting penicillin-binding protein (PBP2a) and mecA gene. Bioorg Chem. 2025 Sep 9;165:108977.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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