SCN2
SCN2 is a esterase-responsive prodrug-based amphiphile composed of SN38 (HY-13704) and di- (triazole-[12]aneN3, N) moiety through a 7‑carbon alkyl chains. SCN2 has excellent self-assembly and reversible siRNA condensation capabilities as well as anti-proliferation activity against cancer cells. SCN2 can be used for synthesis of nanoparticles for drug delivery of lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Cancer
Smiles
CCC1=C2CN3C(C2=NC4=C1C=C(OC(CCCCCCCNC(C5=CC(CN6C=C(CN7CCCNCCCNCCC7)N=N6)=CC(CN8N=NC(CN9CCCNCCCNCCC9)=C8)=C5)=O)=O)C=C4)=CC%10=C(C3=O)COC([C@@]%10(CC)O)=O
Molecular Formula
C63H95N15O7
Molecular Weight
1174.52
References & Citations
[1]Xu DZ, et al. Hybride nanoparticles composed of SN38-modified [12]aneN3 and biotinylated lipids for targeted and synergistic lung Cancer therapy. Bioorg Chem. 2025 Jun 15;160:108411.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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