HDAC-IN-93
HDAC-IN-93 is a HDAC inhibitor with promising total pan-HDAC inhibitory activity. HDAC-IN-93 demonstrates significant broad-spectrum antiproliferative activity across various cancer cell lines. HDAC-IN-93 induces cell apoptosis along with necrosis. HDAC-IN-93 can be used for the studies of prostate cancer and breast cancer[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase; HDAC
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
N/C(C(C=C1)=CC=C1/C=C/C2=CC(C3=CC=CC=C3O2)=O)=N\O
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
References & Citations
[1]Ashraf R, et al. Design and synthesis of novel Hydroxamate and non-Hydroxamate HDAC inhibitors based on Chromone and Quinazolone scaffolds. Bioorg Chem. 2025 Jul 1;161:108514.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2; Caspase 3; HDAC6; HDAC7; HDAC8
Curated Selection
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