SKLB-0266
SKLB-0266 is the negative control of SKLB-0124 (a PRMT6 inhibitor). SKLB-0266 after undergoing methylation modification completely loses its inhibitory activity against PRMT6[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(NCCCC(NC1=CC=C(C2=CN=CC(CN(C)CCN(C)C)=C2)C=C1)=O)CC34C[C@H](C[C@@H]5C4)C[C@H](C5)C3
Molecular Formula
C33H47N5O2
Molecular Weight
545.76
References & Citations
[1]Yang H, et al. Discovery of a first-in-class degrader for the protein arginine methyltransferase 6 (PRMT6) . Bioorg Chem. 2024 Jul;148:107439.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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