MK-251
MK-251 is an orally active anti-arrhythmic agent. MK-251 prevents or modifies ventricular arrhythmias induced in dogs and baboons by tetrafluorethylbutylamine. MK-251 antagonizes the arrhythmias caused by Digoxin in cats. MK-251 at effective doses has little effect on basic cardiovascular parameters such as blood pressure, cardiac output, myocardial contractility and ventricular conduction, thus demonstrating its unique advantages[1].
Product Specifications
CAS Number
36386-71-7
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cardiovascular Disease
Smiles
FC(C1=CC=CC=C1)(C(F)(C2=CC=C(C(C)(C)N)C=C2)F)F
Molecular Formula
C17H17F4N
Molecular Weight
311.32
References & Citations
[1]Torchiana ML, et al. The antiarrhythmic and hemodynamic actions of alpha, alpha-dimethyl-4- (alpha, alpha, beta, beta-tetrafluorophenethyl) benzylamine (MK-251) . J Pharmacol Exp Ther. 1975 Aug;194 (2) :415-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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