PTX-SS-COOH

PTX-SS-COOH is the proform that can be grafted to the sulfhydryl modified gelatin to form the redox sensitive amphiphilic polymer. The nanoparticle (BSA/Gel-SS-PTX/PTX-SS-COOH NPs) demonstrates an excellent anticancer efficiency. PTX-SS-COOH can be applied in the research of targeted delivery for solid tumors (such as breast cancer and melanoma) by utilizing the unique characteristics of the tumor microenvironment (high GSH level) [1].

Product Specifications

CAS Number

[1800077-28-4]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Cancer

Purity

98.75

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCSSCCC(O)=O)=O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C)C)O)OC(C7=CC=CC=C7)=O)=O

Molecular Formula

C53H59NO17S2

Molecular Weight

1046.16

References & Citations

[1]Zhou K, et al. Redox- and MMP-2-sensitive drug delivery nanoparticles based on gelatin and albumin for tumor targeted delivery of paclitaxel. Mater Sci Eng C Mater Biol Appl. 2020 Sep;114:111006.