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Carbonic anhydrase-IN-2

Carbonic anhydrase-IN-2 is an orally active carbonic anhydrase inhibitor. Carbonic anhydrase-IN-2 shows antibacterial effect against various vancomycin-resistant Enterococcus (VRE) strains. Carbonic anhydrase-IN-2 can be used for the research of infection, such as E. faecium[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial; Carbonic Anhydrase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=S(C1=NN=C(S1)NC(CCC2=CC=C(C=C2)C)=O)(N)=O

Molecular Formula

C12H14N4O3S2

Molecular Weight

326.39

References & Citations

[1]Holly KJ, et al. Hit-to-Lead Optimization of Acetazolamide-Based Bacterial Carbonic Anhydrase Inhibitors with Efficacy In Vivo for Treatment of Vancomycin-Resistant Enterococci Septicemia. J Med Chem. 2025 Sep 11;68 (17) :18597-18624.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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