Carbonic anhydrase-IN-2
Carbonic anhydrase-IN-2 is an orally active carbonic anhydrase inhibitor. Carbonic anhydrase-IN-2 shows antibacterial effect against various vancomycin-resistant Enterococcus (VRE) strains. Carbonic anhydrase-IN-2 can be used for the research of infection, such as E. faecium[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Carbonic Anhydrase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=S(C1=NN=C(S1)NC(CCC2=CC=C(C=C2)C)=O)(N)=O
Molecular Formula
C12H14N4O3S2
Molecular Weight
326.39
References & Citations
[1]Holly KJ, et al. Hit-to-Lead Optimization of Acetazolamide-Based Bacterial Carbonic Anhydrase Inhibitors with Efficacy In Vivo for Treatment of Vancomycin-Resistant Enterococci Septicemia. J Med Chem. 2025 Sep 11;68 (17) :18597-18624.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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