Antifungal agent 135
Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against P. capsici and V. mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth[1].
Product Specifications
UNSPSC
12352005
Target
Fungal; Succinate Dehydrogenase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(NN(C(C1=CC=CC(C(F)(F)F)=C1)=O)C2=NC(C(F)(F)F)=CS2)C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3
Molecular Formula
C21H9F12N3O2S
Molecular Weight
595.36
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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