SDH-IN-30

SDH-IN-30 (Compound 7m) is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.34 μM. SDH-IN-30 has potent antifungal activities against Rhizoctonia solani and Sclerotinia sclerotiorum with EC50s of 0.004 and 0.028 μg/mL. SDH-IN-30 also has remarkable protective and curative efficacies against R. solani and significantly inhibits S. sclerotiorum growth on oilseed rape leaves by damaging the fungal cell structure. SDH-IN-30 can be used for fungal infections like rice sheath blight (RSB) and sclerotinia stem rot (SSR) research[1].

Product Specifications

UNSPSC

12352005

Target

Fungal; Succinate Dehydrogenase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C1=CN(C)N=C1C(F)F)NC2=CC=CC=C2/C=C/C3=C(C)C=C(C)C=C3C

Molecular Formula

C23H23F2N3O

Molecular Weight

395.45

References & Citations

[1]Luo B, et al. Discovery of Highly Efficient Novel Potential Succinate Dehydrogenase Inhibitors Containing a Stilbene Group for Management of Sheath Blight of Rice and Sclerotinia Stem Rot of Oilseed Rape. J Agric Food Chem. 2025 Sep 24;73 (38) :23856-23870.