OSBP ligand-Linker Conjugate 1
OSBP ligand-Linker Conjugate 1 is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for OSBP (HY-178035) and a PROTAC linker, which recruits E3 ligases. OSBP ligand-Linker Conjugate 1 can be used for synthesis of PROTAC OSBP Degrader-1 (HY-178034) [1].
Product Specifications
UNSPSC
12352005
Target
Oxysterol-binding Protein-related Protein (ORP) ; Target Protein Ligand-Linker Conjugates
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
O=C(O)COCCOCCCCCCN1N=NC(COC2=CC(/C=C/C3=CC4=C(C(OC)=C3)O[C@]5(C)CC[C@@H](O)C(C)(C)[C@@]5([H])C4)=CC(O)=C2C/C=C(C)\C)=C1
Molecular Formula
C43H59N3O9
Molecular Weight
761.94
References & Citations
[1]Guimard C, et al. Elaboration and profiling of the first OSBP degrader issued from natural Schweinfurthins. Bioorg Chem. 2025 Sep;164:108909.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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