MYC-IN-4
MYC-IN-4 is a MYC inhibitor. MYC-IN-4 impairs MYC/MAX protein-protein interaction (IC50 = 3.06 μM) . MYC-IN-4 inhibits MYC-aberrant PC-3 prostate cancer cells with an IC50 of 0.440 μM. MYC-IN-4 demonstrates potent antitumor efficacy in FVB mice bearing Myc-CaP prostate tumor allografts. MYC-IN-4 can be used for the study of prostate cancer[1].
Product Specifications
UNSPSC
12352005
Target
C-Myc
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
FC(F)(F)C(C=C1)=CC=C1C(O2)=CC3=C2C=CC(C4=CC(C(F)(F)F)=NN4)=C3
Molecular Formula
C19H10F6N2O
Molecular Weight
396.29
References & Citations
[1]Yang L, et al. Benzofuranyl-pyrazole as a Novel Scaffold for In Vitro and In Vivo Potent Anticancer Therapeutics That Directly Disrupt the 'Undruggable' MYC Oncogene and Potentiate Immune Checkpoint Blockage. J Med Chem. 2025 Sep 25;68 (18) :19184-19204.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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