SOS1-IN-24
SOS1-IN-24 (Compound 15) is a SOS1 inhibitor with an IC50 of 0.398 μM. SOS1-IN-24 effectively disrupts SOS1::KRAS12D interaction. SOS1-IN-24 can be used for cancers like pancreatic and colorectal cancer research[1].
Product Specifications
UNSPSC
12352005
Target
SOS1
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Smiles
C[C@@H](NC(C1=CC=CC=C12)=NS2(=O)=O)C3=CC(C(F)(F)F)=CC(N)=C3
Molecular Formula
C16H14F3N3O2S
Molecular Weight
369.36
References & Citations
[1]Bonomo S, et al. Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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