SOS1-IN-24
SOS1-IN-24 (Compound 15) is a SOS1 inhibitor with an IC50 of 0.398 μM. SOS1-IN-24 effectively disrupts SOS1::KRAS12D interaction. SOS1-IN-24 can be used for cancers like pancreatic and colorectal cancer research[1].
Product Specifications
UNSPSC
12352005
Target
SOS1
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Smiles
C[C@@H](NC(C1=CC=CC=C12)=NS2(=O)=O)C3=CC(C(F)(F)F)=CC(N)=C3
Molecular Formula
C16H14F3N3O2S
Molecular Weight
369.36
References & Citations
[1]Bonomo S, et al. Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040679-500 1x 500 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471037-500 1x 500 µL
CD44 Standard (DF1485), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882298-100 1x 100 µL
Cytokeratin 8/18 (rKRT8.18/1346), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details