BTR2038
BTR2038 is a BRD9 degrader. BTR2038 consistis of a BRD9 bromodomain ligand (Bl-7273 analoag), a linker and BTR2000 (HY-172563) . BTR2038 induces targeted degradation of V5-tagged human BRD9. BTR2038 can be used for the study of biological processes and diseases associated with abnormal BRD9 protein function[1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Others
Smiles
O=C(N1CCC[C@@H]1C(N[C@H](CC(O)=O)C(N[C@H](CC(C)C)C(N[C@@H](CSC2)C(N)=O)=O)=O)=O)[C@H](CSC3=CC2=CC=C3)NC(CCCNCC4=C(OC)C=C(C5=CN(C)C(C6=C5C=CN=C6)=O)C=C4OC)=O
Molecular Formula
C50H63N9O11S2
Molecular Weight
1030.22
References & Citations
[1]Phoebe H, et al. Temporal and Spatial Characterization of CUL3KLHL20-Driven Targeted Degradation of BET Family BRD Proteins by the Macrocycle-Based Degrader BTR2004. ACS Chem. Biol. 2025, 20, 9, 2056–2062.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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