OSBP ligand-1
OSBP ligand-1 (Compound 2) is an Oxysterol-binding protein (OSBP) inhibitor. OSBP ligand-1 can be used for synthesis of PROTAC OSBP Degrader-1 (HY-178034) [1].
Product Specifications
CAS Number
[2890760-73-1]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; Oxysterol-binding Protein-related Protein (ORP)
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
C/C(C)=C\CC1=C(O)C=C(/C=C/C2=CC3=C(C(OC)=C2)O[C@]4(C)CC[C@@H](O)C(C)(C)[C@@]4([H])C3)C=C1OCC#C
Molecular Formula
C33H40O5
Molecular Weight
516.67
References & Citations
[1]Guimard C, et al. Elaboration and profiling of the first OSBP degrader issued from natural Schweinfurthins. Bioorg Chem. 2025 Sep;164:108909.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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