TDI-014925
TDI-014925 (Compound 58) is a SARS-CoV-2 methyltransferase nonstructural protein 14 (NSP14) inhibitor with an IC50 of 0.2 nM. TDI-014925 has an antiviral activity with significant microsomal stability and no CYP inhibitory activity. TDI-014925 can be used for COVID-19 research[1].
Product Specifications
CAS Number
[3052313-53-5]
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=C(C=C(N1C)C(NCC2=C3C(C=NN3C)=CC=C2F)=O)S(=O)(N4CCC5=NNC=C5C4)=O
Molecular Formula
C22H24FN7O3S
Molecular Weight
485.53
References & Citations
[1]Miller MW, et al. Discovery, Optimization, and Evaluation of Non-Nucleoside SARS-CoV-2 NSP14 Inhibitors. J Med Chem. 2025 Sep 25;68 (18) :19076-19106.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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