HDAC6-IN-64
HDAC6-IN-64 (Compound 8) is a HDAC6 inhibitor with an IC50 of 11.9 nM. HDAC6-IN-64 has poor cell permeability. HDAC6-IN-64 can be used for chemotherapy of cancers like NSCLC research[1].
Product Specifications
CAS Number
[2837128-29-5]
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1)CN2C(N(C(C3=CC=CC=C32)=O)CCC4=CC=CC=C4)=O)NNCC
Molecular Formula
C26H26N4O3
Molecular Weight
442.51
References & Citations
[1]Huang HC, et al. Establishing a noncanonical zinc-binding group as a selective histone deacetylase inhibitor and possible novel anticancer agent. Bioorg Chem. 2025 Aug 27;165:108917
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC6
Curated Selection
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