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HDAC6-IN-64

HDAC6-IN-64 (Compound 8) is a HDAC6 inhibitor with an IC50 of 11.9 nM. HDAC6-IN-64 has poor cell permeability. HDAC6-IN-64 can be used for chemotherapy of cancers like NSCLC research[1].

Product Specifications

CAS Number

2837128-29-5

UNSPSC

12352005

Target

HDAC

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C=C1)CN2C(N(C(C3=CC=CC=C32)=O)CCC4=CC=CC=C4)=O)NNCC

Molecular Formula

C26H26N4O3

Molecular Weight

442.51

References & Citations

[1]Huang HC, et al. Establishing a noncanonical zinc-binding group as a selective histone deacetylase inhibitor and possible novel anticancer agent. Bioorg Chem. 2025 Aug 27;165:108917

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC6

Frequently Asked Questions

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