BChE/hCA II-IN-1
BChE/hCA II-IN-1 (Compound 20) is a dual-functional inhibitor of Butyrylcholinesterase (BChE) and human carbonic anhydrase II (hCA II) with IC50s of 76.50 and 10.69 μM for BChE and hCA II, respectively. BChE/hCA II-IN-1 can be used for neurodegenerative diseases like Alzheimer's and glaucoma research[1].
Product Specifications
UNSPSC
12352100
Target
Carbonic Anhydrase; Cholinesterase (ChE)
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC(C)C[C@@H](C(O)=O)NS(=O)(C1=CC(S(=O)(N[C@@H](C(O)=O)CC(C)C)=O)=C(C)C=C1OC)=O
Molecular Formula
C20H32N2O9S2
Molecular Weight
508.61
References & Citations
[1]Canoğlu U, et al. Synthesis of novel benzene bissulfonamides with carbonic anhydrase and choline esterase inhibitory properties. Bioorg Chem. 2025 Aug 31;165:108938.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; CA II; CA I
Curated Selection
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