IDO1-IN-28
IDO1-IN-28 (Compound MQ-1) is a Apo-IDO1 inhibitor with an IC50 of 1.29 μM. IDO1-IN-28 selectively targets apo-IDO1 and disrupts heme binding. IDO1-IN-28 can be used for cancers research[1].
Product Specifications
CAS Number
1219296-74-8
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(N1CCC2=C1C=CC=C2)C(NC(NC3=CC=C(Cl)C=C3)=O)CC4=CC=CC=C4
Molecular Formula
C24H22ClN3O2
Molecular Weight
419.90
References & Citations
[1]Yin Y, et al. Identification of a Novel Core Structure of Apo-Ido1 Inhibitors Through Virtual Screening and Preliminary Hit Optimization. J Chem Inf Model. 2025 Sep 22;65 (18) :9723-9737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1
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