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ACS03

ACS03 is a hybrid thiophene-acridine compound. ACS03 induces an increase in lactate dehydrogenase, glutathione S-transferase, and AChE activities. ACS03 has antileishmanial activity. ACS03 exhibits selective anti-cancer effects against colon carcinoma[1].

Product Specifications

CAS Number

[2227022-64-0]

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Glutathione S-transferase; Lactate Dehydrogenase; Parasite

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Cancer; Infection

Smiles

COC(C=CC1=NC2=CC(Cl)=CC=C23)=CC1=C3NC(SC4=C5CCCCC4)=C5C#N

Molecular Formula

C24H20ClN3OS

Molecular Weight

433.95

References & Citations

[1]Lisboa T, et al. Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid. Molecules. 2019 Dec 24;25 (1) :64.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; Leishmania

Curated Selection

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