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α-Obscurine derivative-1

α-Obscurine derivative-1 (Compound 7) is a α-Obscurine (HY-134036) derivative. α-Obscurine derivative-1 inhibits CaV3.1 ion channel current with an IC50 of 0.19 μM. α-Obscurine derivative-1 can be used in the research of neurological disorders[1].

Product Specifications

CAS Number

[3093625-46-5]

UNSPSC

12352005

Target

Calcium Channel; Drug Derivative

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

C[C@@H]1C[C@H]2CC3=C(C=CC(OCC4=CC=CC=C4)=N3)[C@]5(C1)NCCC[C@@]52[H]

Molecular Formula

C23H28N2O

Molecular Weight

348.48

References & Citations

[1]Zhao, et al. Lycopodium alkaloid α-obscurine derivatives and pharmaceutical compositions and applications thereof. CN120329301A. China. 2024-01-18.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

T-type calcium channel

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