α-Obscurine derivative-1
α-Obscurine derivative-1 (Compound 7) is a α-Obscurine (HY-134036) derivative. α-Obscurine derivative-1 inhibits CaV3.1 ion channel current with an IC50 of 0.19 μM. α-Obscurine derivative-1 can be used in the research of neurological disorders[1].
Product Specifications
CAS Number
[3093625-46-5]
UNSPSC
12352005
Target
Calcium Channel; Drug Derivative
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
C[C@@H]1C[C@H]2CC3=C(C=CC(OCC4=CC=CC=C4)=N3)[C@]5(C1)NCCC[C@@]52[H]
Molecular Formula
C23H28N2O
Molecular Weight
348.48
References & Citations
[1]Zhao, et al. Lycopodium alkaloid α-obscurine derivatives and pharmaceutical compositions and applications thereof. CN120329301A. China. 2024-01-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
T-type calcium channel
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