MNOX-E36
MNOX-E36 is a murine-specific analogue of NOX-E36 , an anti-CCL-2 L-RNA aptamer that binds and neutralises the mouse chemokine CCL-2. mNOX-E36 reduces scarring in an experimental murine model of glaucoma filtration surgery (GFS). mNOX-E36 ameliorates lupus nephritis in mice. mNOX-E36 can be used for GFS and lupus nephritis research[1][2].
Product Specifications
UNSPSC
12352208
Target
CCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
[mNOX-E36]
References & Citations
[1]Kulkarni O, et al. Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL- (Fas) lpr mice. J Am Soc Nephrol. 2007 Aug;18 (8) :2350-8.|[2]Lim ST, et al. Inhibition of chemokine MCP-1 with mNOX-E36 reduces scarring in a mouse model of glaucoma filtration surgery. Exp Eye Res. 2026 Jan;262:110735.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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