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Adavosertib acid

Adavosertib (AZD1775; MK-1775) acid (Compound 9) is a derivative of AZD1775 (HY-10993) and can be used for the synthesis of PROTAC[1].

Product Specifications

CAS Number

[2714511-66-5]

Product Name Alternative

AZD1775 acid; MK-1775 acid

UNSPSC

12352005

Target

Drug Derivative; Drug Intermediate

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(CN1CCN(CC1)C2=CC=C(NC3=NC=C4C(N(CC=C)N(C4=N3)C5=CC=CC(C(C)(C)O)=N5)=O)C=C2)O

Molecular Formula

C28H32N8O4

Molecular Weight

544.60

References & Citations

[1]Zhu S, et al. Design, synthesis, and biological evaluation of Wee1 kinase degraders. Eur J Med Chem. 2022 Dec 5;243:114786.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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