Triptolide-6-succinate-β-D-glucose
Triptolide-6-succinate-β-D-glucose (Compound 2) is a glucose-conjugated derivative of Triptolide. Triptolide-6-succinate-β-D-glucose is a tumor-selective prodrug targeting glucose transporters (GLUT). Triptolide-6-succinate-β-D-glucose can induce the degradation of the RPB subunit of RNA polymerase II. Triptolide-6-succinate-β-D-glucose inhibits the proliferation of HEK293T cells with an IC50 value of 268 nM. Triptolide-6-succinate-β-D-glucose can be used for the research of cancer, such as prostatic cancer[1].
Product Specifications
CAS Number
2003231-25-0
UNSPSC
12352005
Target
DNA/RNA Synthesis; Drug Derivative; GLUT
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
Molecular Formula
C30H38O14
Molecular Weight
622.61
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CEP192 CRISPR All-in-one AAV vector set (with saCas9)(Human)
