Triptolide-6-methoxy-β-D-glucose

Triptolide-6-methoxy-β-D-glucose (Compound 6) is a glucose-conjugated derivative of Triptolide (HY-32735) . Triptolide-6-methoxy-β-D-glucose has no effective anti-tumor activity and is mainly used for studying the structural-activity relationship (SAR) of derivatives[1].

Product Specifications

CAS Number

[2003231-33-0]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OCO[C@@H]2[C@@]3(C(C)C)O[C@@]([C@@]4(O[C@]45[C@@]62O[C@@](C[C@]7(C(CO8)=C(CC[C@@]75C)C8=O)[H])6[H])[H])3[H]

Molecular Formula

C27H36O12

Molecular Weight

552.57

References & Citations

[1]He QL, et al. Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation. Angew Chem Int Ed Engl. 2016 Sep 19;55 (39) :12035-9. doi: 10.1002/anie.201606121