CHNQD-00824
CHNQD-00824 is a Terphenyllin (HY-119821) derivative with potent anticancer effect. CHNQD-00824 inhibits the proliferation and migration of cancer cells via DNA damage. CHNQD-00824 triggers apoptosis and inhibits Doxycin Hydrochloride (DOX) -induced liver-specific enlargement in zebrafish embryos. CHNQD-00824 can be used for cancer research, such as liver and breast cancer[1].
Product Specifications
CAS Number
[2222643-74-3]
UNSPSC
12352005
Target
Apoptosis; Caspase; Drug Derivative; PARP
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC1=CC=C(C2=C(C=C(C3=CC=C(C=C3)OCC=C)C(OC)=C2OCC=C)OC)C=C1
Molecular Formula
C26H26O5
Molecular Weight
418.48
References & Citations
[1]Cao XZ, et al. A Terphenyllin Derivative CHNQD-00824 from the Marine Compound Library Induced DNA Damage as a Potential Anticancer Agent. Mar Drugs. 2023 Sep 27;21 (10) :512.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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