Anthranilyl-AMSN

Anthranilyl-AMSN is a potent PqsA inhibitor, with a Kiapp of 170 nM. Anthranilyl-AMSN decreases HHQ and PQS production. Anthranilyl-AMSN can be used in the research of Pseudomonas aeruginosa infections[1].

Product Specifications

CAS Number

[873556-29-7]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CNS(NC(C4=C(O)C=CC=C4)=O)(=O)=O)O3

Molecular Formula

C17H19N7O7S

Molecular Weight

465.44

References & Citations

[1]Ji C, et al. Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa. ACS Chem Biol. 2016 Nov 18;11 (11) :3061-3067.