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CL9 (sodium)

CL9 sodium, a RIG-I-specific RNA aptamer, activates signaling pathways for IFNβ produciton and efficiently blocks viral replication. RIG-I is a cytosolic receptor for non-self RNA that mediates immune responses against viral infections through IFNα/β prod

Product Specifications

UNSPSC

12352208

Target

RIG-I-like receptor (RLR)

Related Pathways

Immunology/Inflammation

Field of Research

Infection

Smiles

[CL9(sodium)]

References & Citations

[1]Hwang SY, Sun HY, Lee KH, Oh BH, Cha YJ, Kim BH, Yoo JY. 5'-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity. Nucleic Acids Res. 2012 Mar;40 (6) :2724-33.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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