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R-2 (sodium)

R-2 sodium is a RNA aptamer that bind to Non-structural protein 1 (NS1) (Kd = 1.92 ± 0.27 nM) . R-2 sodium inhibits the interaction of NS1 with tripartite motif-containing protein 25 (TRIM25), and suppression of NS1 enabled retinoic acid inducible gene I (

Product Specifications

UNSPSC

12352208

Target

Influenza Virus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

[R-2(sodium)]

References & Citations

[1]Woo HM, Lee JM, Kim CJ, Lee JS, Jeong YJ. Recovery of TRIM25-Mediated RIG-I Ubiquitination through Suppression of NS1 by RNA Aptamers. Mol Cells. 2019 Oct 31;42 (10) :721-728.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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