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Protein C aptamer (sodium)

Protein C aptamer sodium is a 44mer-DNA aptamer that the anticoagulant functions of activated protein C. Activated protein C (APC) is a serine protease with anticoagulant, anti-inflammatory, and cytoprotective properties.

Product Specifications

UNSPSC

12352208

Target

Others

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

[ProteinCaptamer(sodium)]

References & Citations

[1]Jaax ME, Krauel K, Marschall T, Brandt S, Gansler J, Fürll B, Appel B, Fischer S, Block S, Helm CA, Müller S, Preissner KT, Greinacher A. Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4. Blood. 2013 Jul 11;122 (2) :272-81.|[2]Müller J, Isermann B, Dücker C, et al. An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor. Chem Biol. 2009;16 (4) :442-451.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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