5β-Cholanic acid-3,6-dione

5β-Cholanic acid-3,6-dione (3,6-Diketo-LCA) is a similar substance to Lithocholic acid (LCA) (HY-B0172) . 5β-Cholanic acid-3,6-dione cannot activate the Vitamin D receptor (VDR), and can be used as a negative control for studying the relationship between LCA derivatives and VDR[1].

Product Specifications

CAS Number

[6868-73-1]

Product Name Alternative

3,6-Diketo-LCA

UNSPSC

12352211

Target

Drug Derivative

Related Pathways

Others

Field of Research

Others

Smiles

C[C@@]12[C@]3([H])[C@](CC([C@]1([H])CC(CC2)=O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C

Molecular Formula

C24H36O4

Molecular Weight

388.54

References & Citations

[1]Adachi R, et al. Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative. J Lipid Res. 2005 Jan;46 (1) :46-57.