DRRM-1
DRRM-1 is a DCAF15-dependent molecular glue degrader of RBM39 and RBM23. dRRM-1 can rescue the self-degradation of DCAF15. dRRM-1 can be used for the research of cancer[1].
Product Specifications
CAS Number
253328-68-6
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=CC=C(C=C1)S(=O)(NC2=CC=C3N=CC=CC3=C2)=O
Molecular Formula
C16H14N2O2S
Molecular Weight
298.36
References & Citations
[1]Hanzl A, et al. E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. J Am Chem Soc. 2023 Jan 18;145 (2) :1176-1184.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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