FL2-14
FL2-14 is a CRBN-dependent, selective GSPT2 molecular glue degrader. FL2-14 downregulates GSPT2, FAM83F, and ZBTB39[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Field of Research
Others
Smiles
O=C1C2=CC=C(NC3=CC=C(OS(N(C)CC4=NC=C(C5CC5)O4)(=O)=O)C=C3)C=C2C(N1C6C(NC(CC6)=O)=O)=O
Molecular Formula
C27H25N5O8S
Molecular Weight
579.58
References & Citations
[1]Govindarajan M, et al. Eco-friendly larvicides from Indian plants: Effectiveness of lavandulyl acetate and bicyclogermacrene on malaria, dengue and Japanese encephalitis mosquito vectors. Ecotoxicol Environ Saf. 2016 Nov;133:395-402. |[2]Nishimura K, et al. A new sesquiterpene, bicyclogermacrene. Tetrahedron Letters, 1969, 10 (36) : 3097-3100.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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