FL2-14
FL2-14 is a CRBN-dependent, selective GSPT2 molecular glue degrader. FL2-14 downregulates GSPT2, FAM83F, and ZBTB39[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Field of Research
Others
Smiles
O=C1C2=CC=C(NC3=CC=C(OS(N(C)CC4=NC=C(C5CC5)O4)(=O)=O)C=C3)C=C2C(N1C6C(NC(CC6)=O)=O)=O
Molecular Formula
C27H25N5O8S
Molecular Weight
579.58
References & Citations
[1]Govindarajan M, et al. Eco-friendly larvicides from Indian plants: Effectiveness of lavandulyl acetate and bicyclogermacrene on malaria, dengue and Japanese encephalitis mosquito vectors. Ecotoxicol Environ Saf. 2016 Nov;133:395-402. |[2]Nishimura K, et al. A new sesquiterpene, bicyclogermacrene. Tetrahedron Letters, 1969, 10 (36) : 3097-3100.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
036178-PE 200 µL
GOT1B, CT (GOLT1B, GOT1A, Vesicle transport protein GOT1B, Golgi transport 1 homolog B, Putative NF-kappa-B-activating protein 470, hGOT1a) (PE) discontinued
Ask
View Details 
51363121 3x 1.0µg DNA
ZNF222 CRISPRa sgRNA lentivector (set of three targets)(Human)
Ask
View Details MBS6383190-01 0.1 mL
ITFG2 (Integrin-alpha FG-GAP Repeat-containing Protein 2, MDS028) (AP)
Ask
View Details 
MBS6383190-02 5x 0.1 mL
ITFG2 (Integrin-alpha FG-GAP Repeat-containing Protein 2, MDS028) (AP)
Ask
View Details 