HDAC-IN-97
HDAC-IN-97 is a PROTAC HDAC6 degrader-6that can be used for synthesis of PROTACs, such as HDAC6 degrader-6 (HY-177758) . HDAC6 degrader-6 is a potent HDAC6 PROTAC degrader with anticancer activity[1].
Product Specifications
CAS Number
[149647-86-9]
UNSPSC
12352211
Target
HDAC; Ligands for Target Protein for PROTAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Field of Research
Cancer
Smiles
O=C(CCCCCCC(O)=O)NO
Molecular Formula
C8H15NO4
Molecular Weight
189.21
References & Citations
[1]Yang K, et al. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chem Biol. 2020 Jul 16;27 (7) :866-876.e8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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