TRPM8 receptor agonist-1
TRPM8 receptor agonist-1 (Example 81) is a TRPM8 receptor agonist. TRPM8 receptor agonist-1 can trigger the inward flow of calcium, sodium and other ions within the cell, causing the cell membrane to depolarize and triggering an action potential. TRPM8 receptor agonist-1 can activate signals related to the swallowing reflex and can be used for the research of oropharyngeal dysphagia[1].
Product Specifications
CAS Number
[2791281-99-5]
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC([C@H]1[C@@](O)(C[C@@H](CC1)C)C(NCCC2=C(C=CC=C2)OCC(N)=O)=O)C
Molecular Formula
C21H32N2O4
Molecular Weight
376.49
References & Citations
[1]Paul Justin MUELLER, et al. Substituted cyclohexanecarboxamides, their preparation and their therapeutic application. WO2022133027A1. 2023-06-16
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPM8
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