PrCP-7414
PrCP-7414 is a prolylcarboxypeptidase (PRCP) inhibitor. PrCP-7414 can block the receptor tyrosine kinase (RTK) signaling pathway mediated by PRCP and the GPCR-RTK crosstalk. PrCP-7414 can inhibit cancer cells proliferation and induce apoptosis. PrCP-7414 can be used for the research of cancer, such as triple negative breast cancer (TNBC) [1].
Product Specifications
CAS Number
[1252037-41-4]
UNSPSC
12352005
Target
Apoptosis; Carboxypeptidase
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
C[C@@H](C1=CC=C(C2=CC=CC=C2)C=C1)[C@H](NC(C(C)(N)C)=O)C(N3[C@@H](CCC3)C(NC4=C5)=NC4=CC(Cl)=C5Cl)=O
Molecular Formula
C31H33Cl2N5O2
Molecular Weight
578.53
References & Citations
[1]Duan L, et al. Prolyl Carboxypeptidase Maintains Receptor Tyrosine Kinase Signaling and Is a Potential Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel) . 2022 Jan 31;14 (3) :739.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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