PROTAC HDAC6 degrader 9
PROTAC HDAC6 degrader 9 is a selective HDAC6 PROTAC degrader. PROTAC HDAC6 degrader 9 can be used for the research cancers related to HDAC6 abnormalities, such as multiple myeloma[1].
Product Specifications
UNSPSC
12352005
Target
HDAC; PROTACs
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NO)C1=CC=C(CN(CCCC)C(NC2=CC=C(OCCCCCCCN3N=NC(CNCC4=CC=C(C5=CC=CC6=C5CN(C(CC7)C(NC7=O)=O)C6=O)C=C4)=C3)C=C2)=O)C=C1
Molecular Formula
C49H57N9O7
Molecular Weight
884.03
References & Citations
[1]Yang K, et al. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chem Biol. 2020 Jul 16;27 (7) :866-876.e8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6
Curated Selection
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