PROTAC HDAC6 degrader 9

PROTAC HDAC6 degrader 9 is a selective HDAC6 PROTAC degrader. PROTAC HDAC6 degrader 9 can be used for the research cancers related to HDAC6 abnormalities, such as multiple myeloma[1].

Product Specifications

UNSPSC

12352005

Target

HDAC; PROTACs

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(NO)C1=CC=C(CN(CCCC)C(NC2=CC=C(OCCCCCCCN3N=NC(CNCC4=CC=C(C5=CC=CC6=C5CN(C(CC7)C(NC7=O)=O)C6=O)C=C4)=C3)C=C2)=O)C=C1

Molecular Formula

C49H57N9O7

Molecular Weight

884.03

References & Citations

[1]Yang K, et al. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chem Biol. 2020 Jul 16;27 (7) :866-876.e8.