GSPT1 degrader-14
GSPT1 degrader-14 is a selective molecular glue GSPT1 degrader. GSPT1 degrader-14 exhibits antiproliferative activity against cancer cells in a CRBN- and GSPT1-dependent manner. GSPT1 degrader-14 can be used for leukemia research[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CCC(CCNS(=O)(NC1=CC=C2C(N(CC2=C1)C3CCC(NC3=O)=O)=O)=O)(C4=CC=CC=C4OC)C
Molecular Formula
C26H32N4O6S
Molecular Weight
528.62
References & Citations
[1]Carter TR, et al. SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues. Bioorg Med Chem. 2024 Apr 15;104:117699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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