GSPT1 degrader-13
GSPT1 degrader-13 is a selective molecular glue GSPT1 degrader. GSPT1 degrader-13 exhibits antiproliferative activity against cancer cells in a CRBN- and GSPT1-dependent manner. GSPT1 degrader-13 can be used for leukemia research[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N1)C(N2CC3=CC(NS(=O)(NCCOC4=C(C=CC=C4C)Cl)=O)=CC=C3C2=O)CCC1=O
Molecular Formula
C22H23ClN4O6S
Molecular Weight
506.96
References & Citations
[1]Carter TR, et al. SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues. Bioorg Med Chem. 2024 Apr 15;104:117699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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